Vhf06655 details

Gene vhfRNAi AccessionVhf06655
Gene SymbolRL21
Gene Description60S ribosomal protein L21
Gene Name in PaperRL21
GroupHost Factor
Ensembl Gene IDENST00000272274 ENST00000311549 ENST00000319826 ENST00000326092 
UniProt IDP46778
Entrez Gene ID6144
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)