Vhf06644 details

Gene vhfRNAi AccessionVhf06644
Gene SymbolHIC1
Gene DescriptionHypermethylated in cancer 1 protein (Hic-1) (Zinc finger and BTB domain-containing protein 29)
Gene Name in PaperHIC1
GroupHost Factor
Ensembl Gene IDENST00000322941 ENST00000399849 ENST00000619757 
UniProt IDQ14526
Entrez Gene ID3090
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)