Vhf06617 details

Gene vhfRNAi AccessionVhf06617
Gene SymbolP2RY6
Gene DescriptionP2Y purinoceptor 6 (P2Y6)
Gene Name in PaperP2RY6
GroupHost Factor
Ensembl Gene IDENST00000349767 ENST00000393590 ENST00000393591 ENST00000393592 ENST00000538328 ENST00000540124 ENST00000540342 ENST00000542092 ENST00000618468 
UniProt IDQ15077
Entrez Gene ID5031
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)