Vhf06602 details

Gene vhfRNAi AccessionVhf06602
Gene SymbolABLM3
Gene DescriptionActin-binding LIM protein 3 (abLIM-3) (Actin-binding LIM protein family member 3)
Gene Name in PaperABLM3
GroupHost Factor
Ensembl Gene IDENST00000309868 ENST00000326685 ENST00000504238 ENST00000506113 ENST00000517451 
UniProt IDO94929
Entrez Gene ID22885
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)