RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf06589 |
| Gene Symbol | HRSL3 | |
| Gene Description | HRAS-like suppressor 3 (HRSL3) (EC 3.1.1.32) (EC 3.1.1.4) (Adipose-specific phospholipase A2) (AdPLA) (Group XVI phospholipase A1/A2) (H-rev 107 protein homolog) (HRAS-like suppressor 1) (HREV107-1) (HREV107-3) (Renal carcinoma antigen NY-REN-65) | |
| Gene Name in Paper | HRSL3 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000323646 ENST00000415826 | |
| UniProt ID | P53816 | |
| Entrez Gene ID | 11145 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |