Vhf06573 details

Gene vhfRNAi AccessionVhf06573
Gene SymbolLMO3
Gene DescriptionLIM domain only protein 3 (LMO-3) (Neuronal-specific transcription factor DAT1) (Rhombotin-3)
Gene Name in PaperLMO3
GroupHost Factor
Ensembl Gene IDENST00000261169 ENST00000320122 ENST00000354662 ENST00000441439 ENST00000447609 ENST00000534946 ENST00000535535 ENST00000537304 ENST00000540445 ENST00000540848 ENST00000541295 ENST00000541846 
UniProt IDQ8TAP4
Entrez Gene ID55885
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)