Vhf06553 details

Gene vhfRNAi AccessionVhf06553
Gene SymbolMRP9
Gene DescriptionMultidrug resistance-associated protein 9 (ATP-binding cassette sub-family C member 12)
Gene Name in PaperMRP9
GroupHost Factor
Ensembl Gene IDENST00000311303 ENST00000497206 ENST00000529084 ENST00000529504 ENST00000532494 ENST00000534418 
UniProt IDQ96J65
Entrez Gene ID94160
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)