Vhf06541 details

Gene vhfRNAi AccessionVhf06541
Gene SymbolTOR2A
Gene DescriptionTorsin-2A (Torsin family 2 member A) (Torsin-related protein 1)
Gene Name in PaperTOR2A
GroupHost Factor
Ensembl Gene IDENST00000373281 ENST00000373284 ENST00000463256 ENST00000463577 ENST00000493439 ENST00000496460 
UniProt IDQ5JU69
Entrez Gene ID27433
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)