Vhf06533 details

Gene vhfRNAi AccessionVhf06533
Gene SymbolAGRG2
Gene DescriptionAdhesion G-protein coupled receptor G2 (G-protein coupled receptor 64) (Human epididymis-specific protein 6) (He6)
Gene Name in PaperAGRG2
GroupHost Factor
Ensembl Gene IDENST00000340581 ENST00000354791 ENST00000356606 ENST00000357544 ENST00000357991 ENST00000360279 ENST00000379869 ENST00000379873 ENST00000379876 ENST00000379878 
UniProt IDQ8IZP9
Entrez Gene ID10149
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)