Vhf06502 details

Gene vhfRNAi AccessionVhf06502
Gene SymbolZBT12
Gene DescriptionZinc finger and BTB domain-containing protein 12 (Protein G10)
Gene Name in PaperZBT12
GroupHost Factor
Ensembl Gene IDENST00000375525 ENST00000375527 ENST00000432044 ENST00000441555 ENST00000458242 ENST00000611032 
UniProt IDQ9Y330
Entrez Gene ID221527
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)