Vhf06498 details

Gene vhfRNAi AccessionVhf06498
Gene SymbolB2L14
Gene DescriptionApoptosis facilitator Bcl-2-like protein 14 (Bcl2-L-14) (Apoptosis regulator Bcl-G)
Gene Name in PaperB2L14
GroupHost Factor
Ensembl Gene IDENST00000266434 ENST00000298566 ENST00000308721 ENST00000396367 ENST00000589718 ENST00000627413 ENST00000628315 ENST00000628783 ENST00000631251 ENST00000631317 
UniProt IDQ9BZR8
Entrez Gene ID79370
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)