RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf06495 |
Gene Symbol | KCNE1 | |
Gene Description | Potassium voltage-gated channel subfamily E member 1 (Delayed rectifier potassium channel subunit IsK) (IKs producing slow voltage-gated potassium channel subunit beta Mink) (Minimal potassium channel) | |
Gene Name in Paper | KCNE1 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000337385 ENST00000399284 ENST00000399286 ENST00000399289 ENST00000416357 ENST00000432085 ENST00000611936 ENST00000621601 | |
UniProt ID | P15382 | |
Entrez Gene ID | 3753 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |