Vhf06495 details

Gene vhfRNAi AccessionVhf06495
Gene SymbolKCNE1
Gene DescriptionPotassium voltage-gated channel subfamily E member 1 (Delayed rectifier potassium channel subunit IsK) (IKs producing slow voltage-gated potassium channel subunit beta Mink) (Minimal potassium channel)
Gene Name in PaperKCNE1
GroupHost Factor
Ensembl Gene IDENST00000337385 ENST00000399284 ENST00000399286 ENST00000399289 ENST00000416357 ENST00000432085 ENST00000611936 ENST00000621601 
UniProt IDP15382
Entrez Gene ID3753
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)