Vhf06487 details

Gene vhfRNAi AccessionVhf06487
Gene SymbolSKIL
Gene DescriptionSki-like protein (Ski-related oncogene) (Ski-related protein)
Gene Name in PaperSKIL
GroupHost Factor
Ensembl Gene IDENST00000259119 ENST00000413427 ENST00000426052 ENST00000458537 
UniProt IDP12757
Entrez Gene ID6498
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)