Vhf06441 details

Gene vhfRNAi AccessionVhf06441
Gene SymbolTENX
Gene DescriptionTenascin-X (TN-X) (Hexabrachion-like protein)
Gene Name in PaperTENX
GroupHost Factor
Ensembl Gene IDENST00000375244 ENST00000451343 ENST00000546684 ENST00000550539 
UniProt IDP22105
Entrez Gene ID7148
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)