Vhf06434 details

Gene vhfRNAi AccessionVhf06434
Gene SymbolRN208
Gene DescriptionRING finger protein 208
Gene Name in PaperRN208
GroupHost Factor
Ensembl Gene IDENST00000391553 ENST00000392827 
UniProt IDQ9H0X6
Entrez Gene ID727800
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)