Vhf06423 details

Gene vhfRNAi AccessionVhf06423
Gene SymbolTPD52
Gene DescriptionTumor protein D52 (Protein N8)
Gene Name in PaperTPD52
GroupHost Factor
Ensembl Gene IDENST00000379096 ENST00000379097 ENST00000448733 ENST00000517427 ENST00000517462 ENST00000518937 ENST00000520527 
UniProt IDP55327
Entrez Gene ID7163
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)