Vhf06422 details

Gene vhfRNAi AccessionVhf06422
Gene SymbolCF136
Gene DescriptionUncharacterized protein C6orf136
Gene Name in PaperCF136
GroupHost Factor
Ensembl Gene IDENST00000293604 ENST00000376471 ENST00000376473 ENST00000383580 ENST00000383581 ENST00000415931 ENST00000417076 ENST00000417649 ENST00000419321 ENST00000422530 ENST00000425581 ENST00000430141 ENST00000447505 ENST00000455682 ENST00000456444 
UniProt IDQ5SQH8
Entrez Gene ID221545
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)