Vhf06410 details

Gene vhfRNAi AccessionVhf06410
Gene SymbolECT2
Gene DescriptionProtein ECT2 (Epithelial cell-transforming sequence 2 oncogene)
Gene Name in PaperECT2
GroupHost Factor
Ensembl Gene IDENST00000232458 ENST00000392692 ENST00000417960 ENST00000441497 ENST00000540509 
UniProt IDQ9H8V3
Entrez Gene ID1894
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)