Vhf06362 details

Gene vhfRNAi AccessionVhf06362
Gene SymbolTRPM1
Gene DescriptionTransient receptor potential cation channel subfamily M member 1 (Long transient receptor potential channel 1) (LTrpC1) (Melastatin-1)
Gene Name in PaperTRPM1
GroupHost Factor
Ensembl Gene IDENST00000256552 ENST00000397795 ENST00000542188 ENST00000559179 ENST00000560658 
UniProt IDQ7Z4N2
Entrez Gene ID4308
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)