Vhf06353 details

Gene vhfRNAi AccessionVhf06353
Gene SymbolPPHLN
Gene DescriptionPeriphilin-1 (CDC7 expression repressor) (CR) (Gastric cancer antigen Ga50)
Gene Name in PaperPPHLN
GroupHost Factor
Ensembl Gene IDENST00000358314 ENST00000395568 ENST00000395580 ENST00000432191 ENST00000449194 ENST00000552761 ENST00000610488 ENST00000613154 ENST00000619544 
UniProt IDQ8NEY8
Entrez Gene ID51535
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)