Vhf06318 details

Gene vhfRNAi AccessionVhf06318
Gene SymbolTCP11
Gene DescriptionT-complex protein 11 homolog
Gene Name in PaperTCP11
GroupHost Factor
Ensembl Gene IDENST00000244645 ENST00000311875 ENST00000373974 ENST00000373979 ENST00000412155 ENST00000418521 ENST00000444780 ENST00000512012 ENST00000611141 
UniProt IDQ8WWU5
Entrez Gene ID6954
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)