Vhf06316 details

Gene vhfRNAi AccessionVhf06316
Gene SymbolABCG1
Gene DescriptionATP-binding cassette sub-family G member 1 (ATP-binding cassette transporter 8) (White protein homolog)
Gene Name in PaperABCG1
GroupHost Factor
Ensembl Gene IDENST00000343687 ENST00000347800 ENST00000361802 ENST00000398449 ENST00000398457 
UniProt IDP45844
Entrez Gene ID9619
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)