Vhf06314 details

Gene vhfRNAi AccessionVhf06314
Gene SymbolH31T
Gene DescriptionHistone H3.1t (H3/t) (H3t) (H3/g)
Gene Name in PaperH31T
GroupHost Factor
Ensembl Gene IDENST00000366696 
UniProt IDQ16695
Entrez Gene ID8290
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)