RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf06285 |
Gene Symbol | L1CAM | |
Gene Description | Neural cell adhesion molecule L1 (N-CAM-L1) (NCAM-L1) (CD antigen CD171) | |
Gene Name in Paper | L1CAM | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000361699 ENST00000361981 ENST00000370055 ENST00000370060 | |
UniProt ID | P32004 | |
Entrez Gene ID | 3897 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |