RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf06282 |
Gene Symbol | SIA7F | |
Gene Description | Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 (EC 2.4.99.-) (GalNAc alpha-2,6-sialyltransferase VI) (ST6GalNAc VI) (ST6GalNAcVI) (hST6GalNAc VI) (Sialyltransferase 7F) (SIAT7-F) | |
Gene Name in Paper | SIA7F | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000291839 ENST00000373141 ENST00000373142 ENST00000373144 ENST00000373146 ENST00000622357 | |
UniProt ID | Q969X2 | |
Entrez Gene ID | 30815 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |