Vhf06276 details

Gene vhfRNAi AccessionVhf06276
Gene SymbolALDOA
Gene DescriptionFructose-bisphosphate aldolase A (EC 4.1.2.13) (Lung cancer antigen NY-LU-1) (Muscle-type aldolase)
Gene Name in PaperALDOA
GroupHost Factor
Ensembl Gene IDENST00000338110 ENST00000395248 ENST00000412304 ENST00000563060 ENST00000564546 ENST00000564595 ENST00000566897 ENST00000569545 
UniProt IDP04075
Entrez Gene ID226
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)