Vhf06267 details

Gene vhfRNAi AccessionVhf06267
Gene SymbolPROL4
Gene DescriptionProline-rich protein 4 (Lacrimal proline-rich protein) (Nasopharyngeal carcinoma-associated proline-rich protein 4)
Gene Name in PaperPROL4
GroupHost Factor
Ensembl Gene IDENST00000228811 ENST00000544994 ENST00000574424 ENST00000576999 ENST00000614435 ENST00000632373 
UniProt IDQ16378
Entrez Gene ID11272
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)