Vhf06266 details

Gene vhfRNAi AccessionVhf06266
Gene SymbolDAPK1
Gene DescriptionDeath-associated protein kinase 1 (DAP kinase 1) (EC 2.7.11.1)
Gene Name in PaperDAPK1
GroupHost Factor
Ensembl Gene IDENST00000358077 ENST00000408954 ENST00000469640 ENST00000472284 ENST00000491893 ENST00000622514 
UniProt IDP53355
Entrez Gene ID1612
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)