Vhf06221 details

Gene vhfRNAi AccessionVhf06221
Gene SymbolMOB3C
Gene DescriptionMOB kinase activator 3C (Mob1 homolog 2C) (Mps one binder kinase activator-like 2C)
Gene Name in PaperMOB3C
GroupHost Factor
Ensembl Gene IDENST00000319928 ENST00000371940 
UniProt IDQ70IA8
Entrez Gene ID148932
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)