RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf06193 |
| Gene Symbol | BRD2 | |
| Gene Description | Bromodomain-containing protein 2 (O27.1.1) (Really interesting new gene 3 protein) | |
| Gene Name in Paper | BRD2 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000374825 ENST00000374831 ENST00000383108 ENST00000395287 ENST00000399527 ENST00000399528 ENST00000399529 ENST00000414731 ENST00000436979 ENST00000438194 ENST00000442863 ENST00000448067 ENST00000449085 ENST00000449118 ENST00000549126 ENST00000552587 | |
| UniProt ID | P25440 | |
| Entrez Gene ID | 6046 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |