Vhf06174 details

Gene vhfRNAi AccessionVhf06174
Gene SymbolPAX1
Gene DescriptionPaired box protein Pax-1 (HuP48)
Gene Name in PaperPAX1
GroupHost Factor
Ensembl Gene IDENST00000398485 ENST00000444366 
UniProt IDP15863
Entrez Gene ID5075
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)