Vhf06145 details

Gene vhfRNAi AccessionVhf06145
Gene SymbolARFG3
Gene DescriptionADP-ribosylation factor GTPase-activating protein 3 (ARF GAP 3)
Gene Name in PaperARFG3
GroupHost Factor
Ensembl Gene IDENST00000263245 ENST00000437119 
UniProt IDQ9NP61
Entrez Gene ID26286
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)