Vhf06141 details

Gene vhfRNAi AccessionVhf06141
Gene SymbolHXB3
Gene DescriptionHomeobox protein Hox-B3 (Homeobox protein Hox-2.7) (Homeobox protein Hox-2G)
Gene Name in PaperHXB3
GroupHost Factor
Ensembl Gene IDENST00000311626 ENST00000460160 ENST00000470495 ENST00000472863 ENST00000476342 ENST00000489475 ENST00000498678 
UniProt IDP14651
Entrez Gene ID3213
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)