Vhf06138 details

Gene vhfRNAi AccessionVhf06138
Gene SymbolESR2
Gene DescriptionEstrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene Name in PaperESR2
GroupHost Factor
Ensembl Gene IDENST00000267525 ENST00000341099 ENST00000344288 ENST00000353772 ENST00000358599 ENST00000553796 ENST00000554572 ENST00000555278 ENST00000557772 
UniProt IDQ92731
Entrez Gene ID2100
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)