Vhf06134 details

Gene vhfRNAi AccessionVhf06134
Gene SymbolTHAS
Gene DescriptionThromboxane-A synthase (TXA synthase) (TXS) (EC 5.3.99.5) (Cytochrome P450 5A1)
Gene Name in PaperTHAS
GroupHost Factor
Ensembl Gene IDENST00000336425 ENST00000411653 ENST00000425687 ENST00000448866 ENST00000458722 
UniProt IDP24557
Entrez Gene ID6916
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)