Vhf06130 details

Gene vhfRNAi AccessionVhf06130
Gene SymbolZN133
Gene DescriptionZinc finger protein 133 (Zinc finger protein 150)
Gene Name in PaperZN133
GroupHost Factor
Ensembl Gene IDENST00000316358 ENST00000377671 ENST00000396026 ENST00000401790 ENST00000402618 ENST00000622607 ENST00000628216 ENST00000630056 
UniProt IDP52736
Entrez Gene ID7692
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)