Vhf06116 details

Gene vhfRNAi AccessionVhf06116
Gene SymbolSCOC
Gene DescriptionShort coiled-coil protein
Gene Name in PaperSCOC
GroupHost Factor
Ensembl Gene IDENST00000338517 ENST00000394203 ENST00000394205 ENST00000506597 ENST00000608372 ENST00000614192 
UniProt IDQ9UIL1
Entrez Gene ID60592
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)