Vhf06100 details

Gene vhfRNAi AccessionVhf06100
Gene SymbolARHGG
Gene DescriptionRho guanine nucleotide exchange factor 16 (Ephexin-4)
Gene Name in PaperARHGG
GroupHost Factor
Ensembl Gene IDENST00000378371 ENST00000378373 ENST00000378378 
UniProt IDQ5VV41
Entrez Gene ID27237
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)