Vhf06085 details

Gene vhfRNAi AccessionVhf06085
Gene SymbolGBRA4
Gene DescriptionGamma-aminobutyric acid receptor subunit alpha-4 (GABA(A) receptor subunit alpha-4)
Gene Name in PaperGBRA4
GroupHost Factor
Ensembl Gene IDENST00000264318 
UniProt IDP48169
Entrez Gene ID2557
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)