Vhf06059 details

Gene vhfRNAi AccessionVhf06059
Gene SymbolTACC2
Gene DescriptionTransforming acidic coiled-coil-containing protein 2 (Anti-Zuai-1) (AZU-1)
Gene Name in PaperTACC2
GroupHost Factor
Ensembl Gene IDENST00000260733 ENST00000334433 ENST00000358010 ENST00000360561 ENST00000369000 ENST00000369005 ENST00000513429 
UniProt IDO95359
Entrez Gene ID10579
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)