RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf06054 |
Gene Symbol | VDR | |
Gene Description | Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor) (Nuclear receptor subfamily 1 group I member 1) | |
Gene Name in Paper | VDR | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000229022 ENST00000395324 ENST00000549336 ENST00000550325 | |
UniProt ID | P11473 | |
Entrez Gene ID | 7421 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |