Vhf06047 details

Gene vhfRNAi AccessionVhf06047
Gene SymbolNCPR
Gene DescriptionNADPH--cytochrome P450 reductase (CPR) (P450R) (EC 1.6.2.4)
Gene Name in PaperNCPR
GroupHost Factor
Ensembl Gene IDENST00000394893 ENST00000412064 ENST00000412521 ENST00000414186 ENST00000418341 ENST00000432753 ENST00000439963 ENST00000449920 ENST00000453773 ENST00000454934 ENST00000461988 
UniProt IDP16435
Entrez Gene ID5447
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
_________________

*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)