RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf06045 |
| Gene Symbol | ITPK1 | |
| Gene Description | Inositol-tetrakisphosphate 1-kinase (EC 2.7.1.134) (Inositol 1,3,4-trisphosphate 5/6-kinase) (Inositol-triphosphate 5/6-kinase) (Ins(1,3,4)P(3) 5/6-kinase) (EC 2.7.1.159) | |
| Gene Name in Paper | ITPK1 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000267615 ENST00000354313 ENST00000556603 ENST00000614271 ENST00000617836 ENST00000626153 | |
| UniProt ID | Q13572 | |
| Entrez Gene ID | 3705 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |