RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf06028 |
| Gene Symbol | LIRA5 | |
| Gene Description | Leukocyte immunoglobulin-like receptor subfamily A member 5 (CD85 antigen-like family member F) (Immunoglobulin-like transcript 11) (ILT-11) (Leukocyte immunoglobulin-like receptor 9) (LIR-9) (CD antigen CD85f) | |
| Gene Name in Paper | LIRA5 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000432233 ENST00000486742 ENST00000611164 ENST00000612266 ENST00000612621 ENST00000613559 ENST00000614299 ENST00000615820 ENST00000616133 ENST00000618711 ENST00000619516 ENST00000620091 ENST00000620692 ENST00000620898 ENST00000621042 ENST00000621482 | |
| UniProt ID | A6NI73 | |
| Entrez Gene ID | 353514 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |