Vhf06022 details

Gene vhfRNAi AccessionVhf06022
Gene SymbolZBT47
Gene DescriptionZinc finger and BTB domain-containing protein 47 (Zinc finger protein 651)
Gene Name in PaperZBT47
GroupHost Factor
Ensembl Gene IDENST00000232974 
UniProt IDQ9UFB7
Entrez Gene ID92999
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)