Vhf05995 details

Gene vhfRNAi AccessionVhf05995
Gene SymbolZSC10
Gene DescriptionZinc finger and SCAN domain-containing protein 10 (Zinc finger protein 206)
Gene Name in PaperZSC10
GroupHost Factor
Ensembl Gene IDENST00000252463 ENST00000538082 ENST00000575108 
UniProt IDQ96SZ4
Entrez Gene ID84891
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)