RNAi screen analysis of viral host genes
Gene | vhfRNAi Accession | Vhf05986 |
Gene Symbol | ERR3 | |
Gene Description | Estrogen-related receptor gamma (ERR gamma-2) (Estrogen receptor-related protein 3) (Nuclear receptor subfamily 3 group B member 3) | |
Gene Name in Paper | ERR3 | |
Group | Host Factor | |
Ensembl Gene ID | ENST00000359162 ENST00000360012 ENST00000361395 ENST00000361525 ENST00000366937 ENST00000366938 ENST00000366940 ENST00000391890 ENST00000408911 ENST00000463665 ENST00000487276 ENST00000493603 ENST00000493748 ENST00000616180 | |
UniProt ID | P62508 | |
Entrez Gene ID | 2104 | |
GO | View | |
Host | Organism | Homo sapiens |
Virus | Virus full name | Poliovirus |
Virus Abbreviation | PV | |
Taxonomy | View | |
Results | Phenotype | Increased infection |
Hits Number* | 124 | |
Confirmed Hits Number | 27 | |
Score | NA | |
Unit | NA | |
Methods | Assay Type | Cell-based |
BioModel Description | HEp-2C and Vero cells | |
Confirmatory Screen Description | ELISA | |
Primary Screen Description# | Z-score of ≥ 3.0 | |
Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
References | Pubmed ID | 26581994 |