RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf05969 |
| Gene Symbol | RPA12 | |
| Gene Description | DNA-directed RNA polymerase I subunit RPA12 (Zinc ribbon domain-containing protein 1) | |
| Gene Name in Paper | RPA12 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000332435 ENST00000359374 ENST00000376782 ENST00000376785 ENST00000383613 ENST00000400659 ENST00000400660 ENST00000400662 ENST00000412396 ENST00000417275 ENST00000417738 ENST00000420100 ENST00000428913 ENST00000429558 ENST00000431032 ENST00000431416 ENST00000432227 ENST00000432545 ENST00000432904 ENST00000433264 ENST00000437373 ENST00000437507 ENST00000441251 ENST00000442585 ENST00000443142 ENST00000443494 ENST00000444027 ENST00000444794 ENST00000446493 ENST00000451875 ENST00000453694 ENST00000455948 | |
| UniProt ID | Q9P1U0 | |
| Entrez Gene ID | 30834 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |