RNAi screen analysis of viral host genes
| Gene | vhfRNAi Accession | Vhf05963 |
| Gene Symbol | DPYL2 | |
| Gene Description | Dihydropyrimidinase-related protein 2 (DRP-2) (Collapsin response mediator protein 2) (CRMP-2) (N2A3) (Unc-33-like phosphoprotein 2) (ULIP-2) | |
| Gene Name in Paper | DPYL2 | |
| Group | Host Factor | |
| Ensembl Gene ID | ENST00000311151 ENST00000521913 ENST00000523027 | |
| UniProt ID | Q16555 | |
| Entrez Gene ID | 1808 | |
| GO | View | |
| Host | Organism | Homo sapiens |
| Virus | Virus full name | Poliovirus |
| Virus Abbreviation | PV | |
| Taxonomy | View | |
| Results | Phenotype | Increased infection |
| Hits Number* | 124 | |
| Confirmed Hits Number | 27 | |
| Score | NA | |
| Unit | NA | |
| Methods | Assay Type | Cell-based |
| BioModel Description | HEp-2C and Vero cells | |
| Confirmatory Screen Description | ELISA | |
| Primary Screen Description# | Z-score of ≥ 3.0 | |
| Note/Comment | A collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production | |
| References | Pubmed ID | 26581994 |