Vhf05940 details

Gene vhfRNAi AccessionVhf05940
Gene SymbolPRAM8
Gene DescriptionPRAME family member 8
Gene Name in PaperPRAM8
GroupHost Factor
Ensembl Gene IDENST00000357367 ENST00000611408 ENST00000614831 ENST00000616484 ENST00000621519 ENST00000631760 ENST00000632222 ENST00000632952 
UniProt IDQ5VWM4
Entrez Gene ID391002
GOView
Host OrganismHomo sapiens
Virus Virus full namePoliovirus
Virus AbbreviationPV
TaxonomyView
Results PhenotypeIncreased infection
Hits Number*124
Confirmed Hits Number27 
ScoreNA
UnitNA
Methods Assay Type Cell-based
BioModel DescriptionHEp-2C and Vero cells
Confirmatory Screen DescriptionELISA
Primary Screen Description#Z-score of ≥ 3.0
Note/CommentA collection of host virus resistance genes that was identified upon silencing increased poliovirus and enterovirus 71 production
References Pubmed ID26581994
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*Replicates that are beyond 2-3 standard deviation values from the mean (Sharma 2009)
#A strong signal/background ratio with low variation in the assay (Zhang 1999)